This version was machine-translated from German and has not been medically reviewed. The authoritative version is the German version.
Fluids, electrolytes & acid-base
19 calculators · maintenance requirements, deficits, sodium, potassium, osmolality, anion gap, compensation
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Fluid calculator
Holliday-Segar maintenance requirement, 24-hour plan for dehydration and volume bolus by AWMF 068-003 -
Urine output ml/kg/h
From urine volume, weight and collection time – with the oliguria stages according to KDIGO (children and neonates) -
Fluid balance
Intake minus output over a period – with urine output in ml/kg/h and balance in % of body weight -
Free water deficit
In hypernatremia: water deficit from sodium, weight and total body water fraction, with correction limit -
Sodium deficit
In hyponatremia: sodium deficit, infusion volume according to Adrogué-Madias and correction limits of the guideline -
Corrected sodium in hyperglycemia
Sodium according to Katz (1.6) and Hillier (2.4) per 100 mg/dl glucose above 100 -
Sodium correction rate
Actual change in sodium from two measurements – compared with the guideline limits -
Potassium intake / potassium replacement
Maintenance requirement, oral and intravenous replacement per kg with maximum rates and concentrations (Daly & Farrington 2013) -
Bicarbonate deficit
Volume of distribution × kg × (target − actual) – with selectable volume of distribution 0.3–0.5 -
Serum osmolality
Calculates from sodium, glucose and urea/BUN – conventional or SI -
Effective osmolality (tonicity)
2 × sodium + glucose – the osmotically effective osmolality without urea -
Osmolal Gap
Measured minus calculated osmolality – with ethanol correction (Purssell 2001) -
Anion gap
Na − (Cl + HCO₃), optionally with potassium – reference range according to Kraut & Madias -
Albumin-corrected Anion Gap
AG + 2.5 × (4.0 − albumin g/dl) according to Figge 1998 -
Delta gap
Anion gap minus 12 – rise in the anion gap relative to the reference value and comparison with the bicarbonate decrease -
Delta ratio
(AG − 12) ÷ (24 − HCO₃) – assessment of mixed acid–base disorders -
Corrected calcium
Albumin-corrected total calcium according to Payne – mg/dl or mmol/l -
Winter's formula
Expected pCO₂ in metabolic acidosis: 1.5 × HCO₃ + 8 ± 2 -
Acid-base compensation calculator
Primary disorder from pH, pCO₂ and HCO₃ – expected compensation according to Berend 2014 and anion gap