This version was machine-translated from German and has not been medically reviewed. The authoritative version is the German version.
Bilirubin
4 calculators · AAP 2022, AAP 2004, AWMF and NICE – Phototherapy and exchange thresholds
Here you will find calculators for assessing bilirubin in newborns using phototherapy and exchange transfusion thresholds. The AAP Bilirubin 2022 calculator (Kemper et al.) applies to newborns from 35 weeks and shows hour-specific thresholds, the escalation-of-care threshold, recommended follow-up and a nomogram with all measurement points. For comparison, the older AAP nomograms of 2004 and the historical German guideline AWMF 024-007 (as of 2015, expired) are available. The calculators are intended as aids for healthcare professionals. Each calculator states its formula and sources.
-
AAP Bilirubin 2022
Newborns ≥ 35 weeks of gestation: phototherapy, escalation and exchange thresholds, follow-up, course -
AAP Bilirubin 2004 (Legacy)
Older nomograms (low, intermediate, high risk) -
Bilirubin per AWMF 024-007 (historical, as of 2015)
German guideline of 2015 (expired): Phototherapy threshold by gestational age and hours of life -
Bilirubin per NICE CG98 (United Kingdom)
Phototherapy and exchange thresholds according to the British guideline, also for preterm infants from 23 weeks
Frequently asked questions
How do I determine the phototherapy threshold according to AAP 2022?
The AAP Bilirubin 2022 calculator provides the hour-specific phototherapy and exchange transfusion thresholds by gestational age and neurotoxicity risk factors. It applies to newborns from 35 weeks onward and also shows the distance of the measured value from the threshold.
What does the escalation-of-care threshold mean for bilirubin?
In the AAP Bilirubin 2022 calculator, the escalation-of-care threshold lies 2 mg/dl below the exchange transfusion threshold. The calculator outputs it together with the distance from the threshold and the recommended follow-up after discharge.
Is the AWMF guideline on hyperbilirubinemia still valid?
The Bilirubin according to AWMF 024-007 calculator reflects the status of 08/2015. The guideline was valid until 12/2019 and has expired, so the calculator serves as a historical reference. The more current calculator is AAP Bilirubin 2022.