This version was machine-translated from German and has not been medically reviewed. The authoritative version is the German version.
Sodium deficit
In hyponatremia: sodium deficit, infusion volume according to Adrogué-Madias and correction limits of the guideline
Scientific basis
Children
The formulas come mainly from studies in adults and are applied unchanged in children; where total body water is involved (water and sodium deficit), the age-appropriate body water fraction is used. According to the European guideline, the sodium correction limits (10 mmol/l per 24 h) also apply to children.
Calculation aid for healthcare professionals: the calculator reproduces what the sources cited assign to the inputs. Clinical assessment and every treatment decision remain with the treating physician. Inputs and results are not stored.
Frequently asked questions
Sodium deficit: What does this calculator compute?
Calculates the sodium deficit (TBW × (target − actual)) and, by the Adrogué-Madias formula, the rise in serum sodium per liter of a chosen infusate as well as the volume for a desired rise – with the upper limits of the European hyponatremia guideline (10 mmol/l in 24 h).
Sodium deficit: Which sources is this calculator based on?
Adrogué HJ, Madias NE: Hypernatremia (N Engl J Med 342:1493–1499) (2000); Adrogué HJ, Madias NE: Hyponatremia (N Engl J Med 342:1581–1589) (2000); Spasovski G, Vanholder R, Allolio B, et al. – Hyponatraemia Guideline Development Group (ESE/ESICM/ERA-EDTA): Clinical practice guideline on diagnosis and treatment of hyponatraemia (Eur J Endocrinol 170:G1–G47) (2014)