This version was machine-translated from German and has not been medically reviewed. The authoritative version is the German version.

ISTH DIC score

Platelets, fibrin markers, prothrombin time, fibrinogen (0–8 points) – ≥ 5 compatible with overt DIC (Taylor 2001)

Platelet count
Fibrin-related marker (D-dimer, fibrin degradation products, soluble fibrin)

The limits for “moderate” and “strong” depend on the test and must be defined by the laboratory.

Prolongation of the prothrombin time
Fibrinogen

Calculation aid for healthcare professionals: the calculator reproduces what the sources cited assign to the inputs. Clinical assessment and every treatment decision remain with the treating physician. Inputs and results are not stored.

Frequently asked questions

ISTH DIC score: What does this calculator compute?

ISTH score for overt disseminated intravascular coagulation (Taylor 2001) in patients with a DIC-associated underlying disease: platelet count (0–2), fibrin-related marker (0/2/3), prolongation of prothrombin time (0–2) and fibrinogen (0–1); ≥ 5 points compatible with overt DIC.

ISTH DIC score: Which sources is this calculator based on?

Taylor FB Jr, Toh CH, Hoots WK, Wada H, Levi M; ISTH Scientific Subcommittee on DIC: Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation (Thromb Haemost 86:1327–1330) (2001)