This version was machine-translated from German and has not been medically reviewed. The authoritative version is the German version.
Absolute lymphocyte count (ALC)
From leukocytes and lymphocyte proportion – age-related reference values (Comans-Bitter 1997) and CTCAE grades
Calculation aid for healthcare professionals: the calculator reproduces what the sources cited assign to the inputs. Clinical assessment and every treatment decision remain with the treating physician. Inputs and results are not stored.
Frequently asked questions
Absolute lymphocyte count (ALC): What does this calculator compute?
Calculates the absolute lymphocyte count and compares it with the age-specific reference intervals (P5–P95) of Comans-Bitter 1997 and with the CTCAE v5.0 grades for lymphopenia.
Absolute lymphocyte count (ALC): Which sources is this calculator based on?
Katsaras G, Koutsi S, Psaroulaki E, Gouni D, Tsitsani P: Neutropenia in Childhood – A Narrative Review and Practical Diagnostic Approach (Hematol Rep 16:375–389) (2024); National Cancer Institute (NCI): Common Terminology Criteria for Adverse Events (CTCAE) Version 5.0 (2017); Comans-Bitter WM, de Groot R, van den Beemd R, et al.: Immunophenotyping of blood lymphocytes in childhood: reference values for lymphocyte subpopulations (J Pediatr 130:388–393) (1997); Merck Manual Professional Edition: Eosinophilia (Hematology and Oncology) (2024)