This version was machine-translated from German and has not been medically reviewed. The authoritative version is the German version.

Local anesthetic maximum dose

Maximum doses for bupivacaine, levobupivacaine, ropivacaine by technique (ESRA/ASRA 2018) – mg and ml per concentration

Details

Body weight (kg)

Technique and substance

Concentration (%)

0.25 % = 2.5 mg/ml; 0.2 % = 2 mg/ml; 0.5 % = 5 mg/ml

Age

Calculation aid for healthcare professionals: the calculator reproduces what the sources cited assign to the inputs. Clinical assessment and every treatment decision remain with the treating physician. Inputs and results are not stored.

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Sources

The European Society of Regional Anaesthesia and Pain Therapy/American Society of Regional Anesthesia and Pain Medicine Recommendations on Local Anesthetics and Adjuvants Dosage in Pediatric Regional Anesthesia (Reg Anesth Pain Med 43:211–216) Suresh S, Ecoffey C, Bosenberg A, et al., 2018. Practice Advisory (full text read)
The Third American Society of Regional Anesthesia and Pain Medicine Practice Advisory on Local Anesthetic Systemic Toxicity (Reg Anesth Pain Med 43:113–123) Neal JM, Barrington MJ, Fettiplace MR, et al., 2018. Practice Advisory (toxicity, lipid therapy)

Scientific basis last reviewed: September 2026.

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Note

Calculation aid for healthcare professionals. Percentiles and z-scores describe the position of a measured value in the reference population; clinical assessment remains with the treating physician.