This version was machine-translated from German and has not been medically reviewed. The authoritative version is the German version.
LDL cholesterol according to Friedewald
LDL from total cholesterol, HDL and triglycerides – with the NHLBI cutoffs for children
Scientific basis
Fasting status
The Friedewald estimate of LDL requires a fasting sample (triglycerides rise postprandially). Non-HDL cholesterol is independent of this and is named by the NHLBI guideline as a screening parameter even without fasting.
Calculation aid for healthcare professionals: the calculator reproduces what the sources cited assign to the inputs. Clinical assessment and every treatment decision remain with the treating physician. Inputs and results are not stored.
Frequently asked questions
LDL cholesterol according to Friedewald: What does this calculator compute?
Estimates LDL cholesterol by the Friedewald formula (LDL = total − HDL − triglycerides/5 in mg/dl or /2.2 in mmol/l), calculates non-HDL cholesterol and classifies both according to the cut-offs of the NHLBI expert panel 2011 for children and adolescents.
LDL cholesterol according to Friedewald: Which sources is this calculator based on?
Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge (Clin Chem 18:499–502) (1972); National Heart, Lung, and Blood Institute; American Academy of Pediatrics: Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents: Summary Report (Pediatrics 128 Suppl 5:S213–S256) – Table 9-1: Acceptable, borderline-high and high plasma lipid concentrations (2011)