This version was machine-translated from German and has not been medically reviewed. The authoritative version is the German version.
eGFR by CKiD U25 (creatinine + cystatin C)
Mean of the creatinine and cystatin C estimates – the most accurate variant of the CKiD U25 equations
Scientific basis
Creatinine depends on muscle mass
Serum creatinine depends on muscle mass: in malnourished children, in neuromuscular disease and in very small children, every creatinine equation overestimates GFR. Cystatin C-based equations are independent of this; in case of doubt, the guideline recommends combining both.
Calculation aid for healthcare professionals: the calculator reproduces what the sources cited assign to the inputs. Clinical assessment and every treatment decision remain with the treating physician. Inputs and results are not stored.